Saturday, June 29, 2013

Antibiotics classes, indications and contraindications

Antibiotics classes, indications and contraindications
Antibiotics classes, indications and contraindications

Antibiotics are molecules that kill, or stop the growth of, microorganisms, including both bacteria and fungi.

Antibiotics may be classified by different ways
Classification on the basis of biological effect:
  • According to spectrum:

    • Broad spectrum
    • Narrow spectrum
  • Classification according to the type of action of antibiotic:
    • Bactericidal: To virulent microorganism to omit the problem from the root. 
    • Bacteriostatic: Slow down the growth and give chance to the body immune response to fight the pathogen.
  • Classification according to chemical structures
  • Classification according to mechanism of action.
  • Classification according to antibiotics contraindications.
Antibiotics Classes, Indications and Contraindications (Medicated Drugs List) :
  1. β-Lactam antibiotics classes, indications and contraindications.
    Examples: penicillins (e.g. amoxicillin), cephalosporins, carbapenems, Monobactams, etc.
  2. Tetracyclines antibiotics classes, indications and contraindications.
    example: tetracycline.
  3. Macrolides antibiotics classes, indications and contraindications.
    example: erythromycin.
  4. Aminoglycosides antibiotics classes, indications and contraindications.
    examples: Gentamicin, Tobramycin, Amikacin.
  5. Quinolones antibiotics classes, indications and contraindications.
    example: Ciprofloxacin (a fluoroquinolones).
  6. Cyclic peptides Glycopeptides antibiotics classes, indications and contraindications.
    examples: Vancomycin, Streptogramins, Polymyxins.
  7. Lincosamides antibiotics classes, indications and contraindications.
     example: clindamycin.
  8. Nitroimidazoles antibiotics classes, indications and contraindications.
  9. Chloramphenicol antibiotics classes, indications and contraindications.
  10. Co-Trimoxazol antibiotics classes, indications and contraindications.
    sulfamethoxazole + trimethoprim.
  11. Nitrofurantoin antibiotics classes, indications and contraindications.
  12. Oxazolidinoes antibiotics classes, indications and contraindications.
    example: Linezolid (Zyvox).
  13. Sulfa antibiotics antibiotics classes, indications and contraindications.
    example: sulfisoxazole.
Antibiotics classes, indications and contraindications


Basic principals of chemical classification:
  • Compounds of similar structures have similar biological activity.
  • Biological activity is frequently due to a structure moieties as – CO-C = X where X is CH2 or N2 or CooH

Antibiotics classes, indications and contraindications

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